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Clinical Trials/NCT03081260
NCT03081260
Completed
Not Applicable

Long-term Evaluation Protocol (12 Months Postoperative) of Total Knee Prostheses Anatomic With Resurfaced Patella Versus Non-resurfaced Patella in Patients Requiring Total Knee Arthroplasty Prospective, Monocentric, Randomized, Open-label Study

Hospices Civils de Lyon1 site in 1 country250 target enrollmentApril 3, 2017
ConditionsArthroplasty

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Arthroplasty
Sponsor
Hospices Civils de Lyon
Enrollment
250
Locations
1
Primary Endpoint
measure of International Knee Society score (IKS score)
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

Total knee arthroplasty is a frequent surgery in France. It currently represents 70,000 interventions per year. The total knee prosthesis is also called tri-compartmental because it allows articulation between the femur and the tibia but also between the femur and the patella.

The patella belongs to the extensor system. It articulates with the femoral trochlea in which it slides. It has an important biomechanical role on the quadriceps strength in addition to allowing flexion-extension movements.

In the case of resurfacing, the joint face of the patella is cut off; A convex polyethylene implant is sealed with cement using studs on the same face.

In case of non-resurfacing, the surgeon leaves in place the cartilage of the patella which will be in direct contact with the femoral prosthetic trochlea.

Both methods have advantages and disadvantages. For some implants, it is recommended to resurface the patella because the implant is not very tolerant with the native patella. Other implants have been designed to be better adapted to the preservation of patellar cartilage.

There is currently no evidence that one method is superior to the other on new generation implants known as "patellar friendly".

It seems necessary to compare both methods in terms of long-term postsurgery results.

Detailed Description

The analysis of the primary endpoint (International Knee Society score (IKS score)) will be based on the assumption that the postsurgery score will be identical in both groups. The t test for independent samples will be used to test this hypothesis.

Registry
clinicaltrials.gov
Start Date
April 3, 2017
End Date
February 28, 2020
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Male or Female (age ≥ 18 years)
  • Diagnosis of knee arthrosis (internal femoro-tibial arthrosis, external femorotibial osteoarthritis, femoro-patellar arthrosis)
  • Indication of total first-line knee arthroplasty

Exclusion Criteria

  • Patient whose surgical complexity requires the placement of a strained prosthesis (ligament laxity, bone loss).
  • Refusal to participate in the study
  • Pregnant women, parturients or nursing mothers
  • Persons deprived of their liberty by a judicial or administrative decision, persons subject to psychiatric care, persons admitted to a health or social institution for purposes other than research
  • Minor Patients
  • Major persons who are subject to a legal protection measure or are unable to express their consent
  • Patient not affiliated to a social security scheme
  • Patient participating in other interventional research excluding routine care studies not interfering with analysis of primary endpoint

Outcomes

Primary Outcomes

measure of International Knee Society score (IKS score)

Time Frame: 12 months after surgery

The comparison of the IKS (International Knee Society) scores (2011 version) will be done between both groups.

Secondary Outcomes

  • Measure of the forgotten joint score(12 months after surgery)
  • abnormality of the patellar stroke(12 months after surgery)

Study Sites (1)

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