A randomised clinical trial of vitamin D to improve cognition in people at risk of dementia

niversity of Exeter0 个研究点目标入组 685 人开始时间: 2018年7月23日最近更新: 2024年7月22日

适应症

试验速览

暂无简介。

•Current inclusion criteria as of 23/04/2020:
•1. Age 50 and over
•2. Already registered as a participant on the PROTECT study
•3. Fulfilling research criteria for dementia risk: Either (1) Performing at least one Standard Deviation below age-matched population norms in two cognitive tests as measured using the validated PROTECT and online cognitive test battery; and/or (2) Reporting subjective memory concerns; and/or (3) Reported family history of dementia
•4. Fulfilling criteria for vitamin D deficiency risk: Defined by a self-reported scale to be completed on registration.
•5. Access to a computer and the internet.
•Previous inclusion criteria:
•1. Aged 50 years and over
•2. Already registered as a participant on the PROTECT study
•3. Fulfilling the AACD criteria: performing at least standard deviation below age-matched population norms in two cognitive tests, as measured using the validated PROTECT and CogTrackTM online cognitive test batteries
•4. Fulfilling criteria for vitamin D deficiency risk (defined by a self-reported scale to be completed upon registration (based on Annweiler et al., 2017)
•5. Access to a computer and the internet

•1. Diagnosed with dementia
•2. Already participating in another active interventional clinical trial
•3. Regularly taking any supplement containing vitamin D:
•3.1. If the supplement is prescribed for a pre-existing condition, the participant will be excluded
•3.2. If the supplement is bought over the counter, the participant will have the option of stopping the supplement and re-registering for the trial after a 28 day washout period
•4. Prescribed the medication Digoxin (Lanoxin)

发起方

niversity of Exeter