Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty
Not Applicable
Completed
- Conditions
- Prosthesis-Related Infections
- Interventions
- Other: Oral Antibiotics
- Registration Number
- NCT01760863
- Lead Sponsor
- Rush University Medical Center
- Brief Summary
The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative antibiotic only. Patients will be monitored for re-infection following hospital discharge, defined as deep infection of the joint space/capsule that requires return to the operating room within 24-months of the re-implantation procedure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 185
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Oral Antibiotics Oral Antibiotics Oral antibiotics for 3 months; recommendation for antibiotics will be made by an infectious disease specialist.
- Primary Outcome Measures
Name Time Method Infection Rate 24 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (4)
Rush University Medical Center
🇺🇸Chicago, Illinois, United States
Central DuPage Hospital
🇺🇸Winfield, Illinois, United States
Vanderbilt
🇺🇸Nashville, Tennessee, United States
Rothman Institute
🇺🇸Philadelphia, Pennsylvania, United States