Endoscopic Management of Non-anastomotic Biliary Strictures Following Liver Transplantation.

Recruiting

• Conditions: Ischemic Cholangiopathy; Non-anastomotic Biliary Stricture; Biliary Stricture; Liver Transplant Disorder; Biliary Stents (Plastic)

• Registration Number: NCT05761483
• Lead Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Brief Summary

The study will evaluate the results of endoscopic treatment of NON-anastomotic biliary strictures following liver transplantation

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-12
• Study First Submitted: 2023-02-25
• Study First Submitted QC: 2023-03-07
• Study First Posted: 2023-03-09
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-12
• Last Update Posted: 2024-11-13
• Primary Completion: 2026-10-31
• Study Completion: 2028-01-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age > 18
• Non anastomotic biliary strictures diagnosed by direct cholangiogram (T-tube) or MRCP
• Stricture involving the hepatic hilum until secondary branches
• Increase of liver function tests
• Signature of the informed consent

Exclusion Criteria

• Previopus endoscopic or percutaneous treatments
• Patient candidate to metal stents placement
• Previous surgery resulting in altered anatomy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of endoscopic treatment of non-anastomosis biliary strictures	2 Years follow-up	Evaluate biliary stricture resolution rate

Trial Locations

Locations (1)

Fondazione Policlinico Gemelli IRCCS; 🇮🇹 Roma, RM, Italy