Culture-based tailored therapy as primary treatment of Helicobacter pylori infectio

Not Applicable

• Conditions: Diseases of the digestive system

• Registration Number: KCT0004877
• Lead Sponsor: Asan Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 April 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 312

Inclusion Criteria

patients with upper GI symptom
- patients with suspected peptic ulcer disease or upper GI neoplasm
- Those who need an upper GI endoscopy for gastric cancer screening
- Those who have confirmed Helicobacter pylori infection through culture test
- A person who consented to participate in this study and voluntarily signed a written consent

Exclusion Criteria

- patients who have H.pylori eradication history
- patients who received esophagectomy, gastrectomy, or duodenectomy
- Those who have a history of allergies to test drugs
- acute GI bleeding patients
- Persons who have taken proton pump inhibitors or histamine receptor antagonists within 4 weeks prior to upper gastrointestinal endoscopy, or who need to take proton pump inhibitors or histamine receptor antagonists within 4 weeks before randomization and until the end of the study participation period after randomization.
- Those who took antibiotics or bismuth within 4 weeks prior to upper gastrointestinal endoscopy, or who need to take antibiotics or bismuth within 4 weeks before randomization and until the end of the study period after randomization
- Those who need to take oral or intravenous steroids during the study period
- Women who are pregnant, lactating, or women of childbearing potential have not undergone infertility surgery or are unwilling to use effective methods of contraception during the trial.
- Those who fail to comply with the planned visit schedule or follow the test procedure
- A person who has a health risk or is difficult to evaluate the purpose of the trial by the investigator's judgment
- Those who fall under the following conditions;
Infectious mononucleosis, patients with central nervous system infection, patients with blood disease or history, patients with organic neurological disorders, patients with genetic problems such as galactose intolerance and Lapp lactose deficiency or glucose-galactose uptake, QT prolongation or ventricular arrhythmia ( Patients with a history of Torsades de pointes)

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Eradication of H. pylori

Secondary Outcome Measures

Name	Time	Method
compliance and side effect of regimen