Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 115
- 试验地点
- 1
- 主要终点
- Myocardial blood volume
研究概览
简要总结
This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years.
- •Available for testing performed in Rochester, MN.
- •Willing to undergo both an echocardiogram with RTMPE and CMR.
- •Study subject providing consent.
排除标准
- •Adults < 18 years.
- •BMI <30 kg/m^
- •Hypertension.
- •Diabetes Mellitus.
- •Cardiomyopathy or structural heart disease.
- •Known coronary artery disease or history of myocardial infarction.
- •Contraindication to echo enhancement agent or gadolinium administration such as an allergy.
- •Renal GFR < 50 mL/mL.
- •Females who are pregnant.
- •Subject unwilling to consent.
研究组 & 干预措施
Healthy adults
Healthy adults will have blood flow to the heart evaluated using s Real-Time Myocardial Echocardiography (RTMPE) and magnetic resonance image (MRI) to the heart.
干预措施: Real-Time Myocardial Echocardiography (RTMPE) (Diagnostic Test)
Healthy adults
Healthy adults will have blood flow to the heart evaluated using s Real-Time Myocardial Echocardiography (RTMPE) and magnetic resonance image (MRI) to the heart.
干预措施: Magnetic resonance image (MRI) (Diagnostic Test)
结局指标
主要结局
Myocardial blood volume
时间窗: Baseline
Ratio in systole and diastole (MBVs/MBVd) by real-time myocardial perfusion echocardiography (RTMPE)
次要结局
未报告次要终点
研究者
Courtney E. Bennett
Principal Investigator
Mayo Clinic