Comparison of 3 in Vivo Microscopic Imaging Techniques for the Diagnosis of Pigmented Tumors. Monocentric Retrospective Study of 170 Tumors
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Basal Cell Carcinoma
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Enrollment
- 161
- Locations
- 1
- Primary Endpoint
- To compare the the relevance of each technique for the diagnostic of pigmented lesions.
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Reflectance confocal microscopy (RCM) is the reference in vivo imaging technique for identifying malignant melanocytic tumors prior to surgical excision. However, it is not widely used due to its high cost and highly technical and time-consuming nature.
In addition to Reflectance confocal microscopy (RCM), it currently use 2 less expensive dermatoscopes that also allow in vivo diagnosis: super-high magnification dermoscopy (D400) and Fluorescence-Advanced videodermatoscopy (FAV).
Detailed Description
Several studies have demonstrated their interest in the in vivo diagnosis of melanocytic tumors, but without any comparison between these methods. In our current practice, many patients have benefited from these 3 imaging modalities for benign and malignant lesions. Therefore, our aim is to analyze these images and compare their performance in the diagnosis of benign and malignant pigmented lesions.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with a pigmented skin lesion of more than 3mm diameter which have benefited systematically of all 3 imaging techniques at the same time, followed by either a surgical excision or annual imaging monitoring.
Exclusion Criteria
- •Bad quality images
- •Insufficient number of images
- •Uncertain diagnosis given by the pathologist
Outcomes
Primary Outcomes
To compare the the relevance of each technique for the diagnostic of pigmented lesions.
Time Frame: Day 1
The nature of the tumor is diagnosed by the imaging technique.
Secondary Outcomes
- Comparison of performance of imaging techniques(Day 1)