Mesoprostol and Dilapen in the preparation of the cervix for abortio

Phase 3

Conditions: Medical abortion in first and second trimester.
(Induced) termination of pregnancy with unspecified complications
O04.80

Registration Number: IRCT20200603047648N1

Lead Sponsor: Karaj University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 196

Inclusion Criteria

Age over 18 years for mothers
Less or equal pregnancy age 24 weeks based on (LMP) and ultrasound of the first 3 months of pregnancy
Patient satisfaction to participate in the study
Legal permission for abortion is from the relevant authorities

Exclusion Criteria

Patients under 18 years of age
Contraindications to the use of misoprostol (drug allergy, active asthma, heart disease, renal failure or glaucoma)
Active genital infection
Structural disorders of the uterus and bladder
Cervical cancer
History of cervical surgery

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cervical dilatation rate. Timepoint: Before surgery and after general anesthesia. Method of measurement: Examination by a specialist.;Feeling sick. Timepoint: Before surgery and after general anesthesia. Method of measurement: Examination by a specialist doctor based on a five-digit criterion (without discomfort, with discomfort, relatively uncomfortable, very uncomfortable, unbearable).;Servicing preparation time. Timepoint: After receiving the drug until the start of surgery. Method of measurement: Examination by a specialist.

Secondary Outcome Measures

Name	Time	Method
Side effects( include vaginal pain, pressure on the bladder, diarrhea and vaginal bleeding, and incomplete miscarriage.). Timepoint: Before general anesthesia, after the procedure and the patient regained consciousness. Method of measurement: Examination by a specialist doctor, ultrasound (if you have symptoms in favor of incomplete abortion once before discharge).;Cervical consistency. Timepoint: Before surgery and after general anesthesia. Method of measurement: Examination by a specialist doctor based on three-digit criteria (according to the surgeon, soft, medium, hard).