NCT04560959Unknown1 期
An Atlas of Cerebral Responses to the Stimuli of the tACS Recorded by SEEG
适应症
试验速览
- 阶段
- 1 期
- 入组人数
- 30
- 主要终点
- Changes of intracranial activities
研究概览
简要总结
By analyzing the SEEG recordings, we explore the range of cortical functional responses to strings of 77.5Hz stimulations delivered by tACS,
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All epileptic patients that would receive the implantation of SEEG electrodes, regardless of the seizure locations;
- •There was no metal implantation before;
- •Eligible for MRI examination;
- •No other lesional neurological disorders;
- •Could be well informed by the study protocols.
排除标准
- •Suffered from any other mental illnesses prior to the enrollment;
- •Those suffering from the serious or unstable organic diseases;
- •Pregnant or lactation women, and those who have a plan of pregnant;
- •Patients with central nervous system tumors, acute brain injury or infection;
- •Skin injured, or allergic to the exposure of the conductive gel;
- •Those with implanted devices;
- •Those who received modified electrical convulsive therapy, or TMS within the recent one month;
- •The score of item 3 (suicidal item) in HAMD-17 equal or greater than 3;
- •Enrolled in any other on going trials;
- •Other situations evaluated by the researchers as inappropriate to the enrollment
结局指标
主要结局
Changes of intracranial activities
时间窗: Within 250 ms immediately after the stimulation.
The change of the power in a band of 0-200 HZ according to the intracranial EEG recording.
次要结局
- Frequency of the epileptic discharges(50 minutes during the stimulation and 50 minutes of the interictal baseline before the intervention during the same hour of the day)
- Event related potential (ERP)(Baseline: 24 hours before the tACS intervention; Observation: Immediately after the end of the tACS intervention.)
研究者
相似试验
Unknown
不适用
EEG Studies of Sensory Processing in Autistic ChildrenAutismNCT00319722Massachusetts General Hospital130
招募中
不适用
Analysis of cerebral cortical activity and functional connectivity using functional MRI in PPPD(Persistent Postural-Perceptual Dizziness) patientsKCT0007452Jeonbuk National University Hospital40
Unknown
不适用
Electrophysiology of Brain Activity During Electrode Implantation in Patients Treated With Deep Brain StimulationEpilepsyParkinson DiseaseDepressionObsessive-Compulsive DisorderNCT03874611University Hospital, Grenoble125
已完成
不适用
Analysis of Electrocorticographic SignalsEpilepsyNCT03785028University of Wisconsin, Madison5
Unknown
不适用
ABR Characteristics and Salivary Cortisone Concentration in Noise-exposed WorkersNoise Induced Hearing LossSensorineural Hearing LossAuditory Nerve LesionNCT04183361University Hospital "Sestre Milosrdnice"100