Tobacco Treatment in the Context of Lung Cancer Screening

Not Applicable

Completed

• Conditions: Smoking Cessation
• Interventions: Behavioral: Text messaging plus nicotine replacement therapy; Other: Standard Care at Lung Cancer Screening

• Registration Number: NCT03927989
• Lead Sponsor: Medical University of South Carolina

Brief Summary

The proposed study will test a medication plus text messaging intervention specifically designed for lung cancer screening patients. Half of the patients will receive standard of care, and half will receive the treatment intervention.

Detailed Description

Screening for lung cancer at earlier, more treatable stages has the potential to reduce mortality from the U.S.'s most deadly cancer. Annual lung cancer screening with low-dose computed tomography is now recommended for high risk individuals based on age and smoking history. This study will evaluate a smoking cessation intervention for lung cancer screening patients. We will evaluate quit rates after a standard intervention (brief counseling session at time of lung cancer screening) versus a dual nicotine replacement therapy (NRT) and gain-framed text messaging intervention.

Study Timeline

• Study Start: 2019-04-15
• Study First Submitted: 2019-04-23
• Study First Submitted QC: 2019-04-23
• Study First Posted: 2019-04-25
• Primary Completion: 2023-10-19
• Study Completion: 2024-02-01
• Status Verified: 2024-10
• Results First Submitted: 2024-10-02
• Results First Submitted QC: 2024-10-02
• Last Update Submitted: 2024-10-02
• Results First Posted: 2024-11-22
• Last Update Posted: 2024-11-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Treatment Arm	Text messaging plus nicotine replacement therapy	Advice to quit and brief discussion of tobacco use plus dual nicotine replacement therapy plus 8 weeks of gain-framed text messages tailored to lung cancer screening patients
Standard Care	Standard Care at Lung Cancer Screening	Advice to quit and brief discussion of tobacco use

Primary Outcome Measures

Name	Time	Method
End of Treatment Abstinence Rates	Week 8 (end of treatment)	7-day point prevalence abstinence

Secondary Outcome Measures

Name	Time	Method
End of Study Abstinence Rates	3-month follow-up	Effect size estimates at End of Study

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States