Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)

Not Applicable

Completed

• Conditions: Hiv; Tobacco Smoking

• Registration Number: NCT05295953
• Lead Sponsor: Gopalkumar Rakesh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-2-10
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria: Potential participants will be<br><br> - Patients enrolled in the Bluegrass Clinic<br><br> - 18-60 years of age<br><br> - Male or female gender<br><br> - Able to read, understand and communicate in English<br><br> - Willing to adhere to the general rules of the Bluegrass Clinic/SMARTClinic/Beyond<br> Birth Clinic<br><br> - Willing and able to abstain from drug use other than Suboxone<br><br> - Exhaled breath on day of study carbon monoxide (CO) < 5 ppm<br><br> - Stabilized on maintenance buprenorphine if having comorbid opioid use disorder.<br><br>Exclusion Criteria:<br><br> - Positive pregnancy test for females, traumatic brain injury, history of seizure<br> disorder, history of or current diagnosis of schizophrenia, intracranial metal<br> shrapnel.<br><br> - Previous adverse effect with TMS.<br><br> - Sub-threshold consistency while performing behavioral tasks.<br><br> - Failure to show baseline attentional bias to smoking versus neutral cues.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gaze Fixation on Smoking Cues;Gaze Fixation on Smoking Cues;Craving for cigarettes;Craving for cigarettes

Secondary Outcome Measures

Name	Time	Method
Functional connectivity changes;Functional connectivity changes