Comparing of Different Biomarkers From Vena Rectalis Superior and Vena Cubiti in Patients Undergoing Low Anterior Resection for Rectum Cancer

• Conditions: Rectal Cancer

• Registration Number: NCT01706809
• Lead Sponsor: Odense University Hospital

Brief Summary

The primary aim of the present study is to investigate different biomarkers like VEGF, EVGF and others ability to predict time to recidive and progressions free survival.

Detailed Description

Patients undergoing LAR for rectum cancer is subjected. Preoperative blood samples from vena rectalis superior and vena cubiti is collected, as well as biopsies from tumor. Preoperative and after 3 month peripheral blood samples is collected.

A total of 50 patients will be included in this study.

The study is approved by the local scientific ethical committee No. S-20100006

Study Timeline

• Study Start: 2011-09
• Study First Submitted: 2012-10-11
• Study First Submitted QC: 2012-10-12
• Study First Posted: 2012-10-15
• Status Verified: 2014-02
• Last Update Submitted: 2014-02-04
• Last Update Posted: 2014-02-05
• Primary Completion: 2015-09
• Study Completion: 2015-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Histological verified cancer
• The cancer must be located in rectum maximum of 15 cm.
• Age above 18

Exclusion Criteria

• Disseminated cancer
• Perioperative radio-chemotherapy
• Laparoscopy surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary aim of the present study is to investigate different biomarkers like VEGF, EVGF and others ability to predict time to recidive and progressions free survival.	after the study is complete

Trial Locations

Locations (1)

Vejle hospital; 🇩🇰 Vejle, Denmark