Important Data on COVID-19 Profile in Africa

Completed

• Conditions: Coronavirus Infection; Africa

• Registration Number: NCT04847817
• Lead Sponsor: Centre de Recherche Médicale de Lambaréné

Brief Summary

The purpose of this study is to Understand the natural history of Coronavirus 2019 (COVID-19) infection to better define the period of infectiousness and transmissibility and to establish biobanks of COVID-19 blood and mucosal samples.

Detailed Description

In this study ,the participants will be enrolled sequentially in the COVID-19 care referral centers. The infected hospitalized patient will be identified by the physicians in hospital. After the patient has given his/her informed consent the permission will be sought from him to approach his household contacts. The household contacts will be screened, and included in the study.

Patients hospitalized and positive for COVID-19 by PCR and their household contacts of all ages and gender (40% minimum of female), will be enrolled upon receipt of written informed consent.

Study Timeline

• Study Start: 2020-08-01
• Study First Submitted: 2020-10-16
• Status Verified: 2021-04
• Study First Submitted QC: 2021-04-13
• Study First Posted: 2021-04-19
• Primary Completion: 2021-12-31
• Study Completion: 2022-03-01
• Last Update Submitted: 2022-07-18
• Last Update Posted: 2022-07-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 574

Inclusion Criteria

• Molecular (PCR) confirmed COVID-19 patients hospitalized in referral centers,
• Household contacts of hospitalized COVID-19 patient,
• Provided signed informed consent.

Exclusion Criteria

• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
clinical and biological parameters of COVID-19	14 days	Infection and disease progression - Pattern of virus transmission
SARS-CoV-2 transmissibility	14 days	proportion of household contact who will become positive for SARS-COV2 using PCR

Trial Locations

Locations (2)

Centre de Recherches Médicales de Lambréné; 🇬🇦 Lambaréne, Gabon

Centre de Recherches Médicales de Lammbaréné; 🇬🇦 Lambaréné, Moyen- Ogooué, Gabon