Acupuncture and Cognitive Impairment in MS

Not Applicable

• Conditions: Multiple Sclerosis.; Multiple sclerosis

• Registration Number: IRCT20220101053582N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients with relapsing-remitting multiple sclerosis
Expanded disability status scale (EDSS) = 5.5
Age 18 to 55 years
Sign the written informed consent

Exclusion Criteria

History of cognitive impairment caused by other chronic or malignant disease
Acute relapse or corticosteroid therapy in the last 30 days before inclusion
Previous use of acupuncture or using any herbal or other alternative treatments
Pregnancy or breastfeeding

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Score of cognitive functioning assessment test. Timepoint: Measurement of cognitive function before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Brief International Cognitive Assessment for multiple sclerosis (BICAMS) questionnaire.

Secondary Outcome Measures

Name	Time	Method
Score of Sleep Quality index. Timepoint: Before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Pittsburgh Sleep Quality index questionnaire.;Score of psychological problems checklist. Timepoint: Before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Symptom Checklist 90- Revised questionnaire.;Score of fatigue severity. Timepoint: Before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Fatigue severity scale questionnaire.