Cognitive Remediation in Older Inpatients with Schizophrenia: a Randomized Controlled Trial
- Conditions
- Mental and behavioral disorders
- Registration Number
- KCT0002609
- Lead Sponsor
- Yongin Mental Hospital
- Brief Summary
Cognitive remediation (CR) was easily provided and well received (drop-out rates = 5.3%) by older psychiatric inpatients. Compared to the Psychiatric Rehabilitation Only (PR-Only) or Treatmet as Usual (TAU) patients, patients in the CR + PR group showed greater improvement in executive functioning. Compared to TAU patients, CR + PR and PR-only patients showed greater improvement in logical memory. More patients in the CR + PR group improved clinically significantly in executive functioning and logical memory, compared with the PR-only and TAU patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 57
The diagnoses of the 57 inpatients with schizophrenia (32 males and 25 females) were confirmed by the Structured Clinical Interview for Diagnostic and Statistical Manual of Menal Disorders-Fourth Edition (DSM-IV) Axis I disorders. All patients had been on stable medication regimens for the previous 30 days.
Participants were excluded if they had any of the following: substance use, serious traumatic brain injury or other neurological disorder, or acute psychiatric symptoms.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eurocognition(Attention, Processing spped: Trail making test A(TMT-A), Coding. Working memory: letter-number sequencing test. Verbal logical memory: Wechsler Memory Scale (WMS) logical memory I,II. Executive functioning: Wisconsin card sorting test(WCST), Trail making test B(TMT-B)
- Secondary Outcome Measures
Name Time Method Psychiatric Symptoms: Positive and Negative Syndrome Scale (PANSS), Premodbid IQ estimate: Wechsler Adult Intelligent Scale -Fourth Edition (WAIS-IV) information subscale