NCT00730873已完成不适用
Fatty Liver and Obstructive Sleep Apnea
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 2
- 主要终点
- Reduction in fatty liver changes on computerized tomography
研究概览
简要总结
Non-alcoholic fatty liver disease is associated with obstructive sleep apnea. Abnormalities in liver enzymes can improve following continuous positive airway pressure in patients with obstructive sleep apnea. Computerized tomography can be used to quantify fatty liver changes. We hypothesize that continuous positive airway pressure can reduce morphologic fatty liver changes in patients with obstructive sleep apnea and non-alcoholic fatty liver, an that this reduction can be evident using computerized tomography
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Obstructive sleep apnea, defined as AHI>5/h
排除标准
- •Consumption of more than 20 grams of alcohol per 24 h
- •Known autoimmune disease
- •Usage of known hepatotoxic drugs
- •Medical history positive for viral hepatitis or other chronic liver disease
结局指标
主要结局
Reduction in fatty liver changes on computerized tomography
时间窗: Within 1-2 years
次要结局
- Improved liver enzymes abnormalities(Within 1-2 years)
研究者
研究点 (2)
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