Effect of Preoperative Oral Carbohydrate Loading on Insulin Resistance Assessed using HOMA -IR in Elective Lower Segment Cesarean Section Patients done under Spinal Anesthesia - A Randomized Prospective Parallel Arm Double Blinded Controlled Trial

A single dose of carbohydrate reduces postoperative insulin resistance, glyconeogenesis, glycogenolysis, and lipolysis

It also minimizes muscle protein catabolism and allows glucose accumulation in the liver to be stored as glycogen.

The aim of preoperative administration of carbohydrate solution before surgical intervention is to increase glycogen storage in the body and reduce possible tissue damage and insulin resistance.

Administration of these liquids during the perioperative period has been reported to increase patient comfort, reduce the patient’s anxiety level, and shorten the hospital stay.

Aim is To compare the effect of preoperative oral carbohydrate drink on insulin resistance using HOMA –IR in elective lower segment caesarean section patients under spinal anaesthesia with ERAS recommended perioperative fasting guidelines vs conventional fasting method.Single centre – parallel arm , prospective study

Double blinded (outcome assessor/primary investigator)

Randomized controlled trial

Group I included patients randomized to receive oral carbohydrate drinks (CHO)

Group II included patients randomized to serve as controls and receive standard fasting (SF).