Vitamin D and Stroke
Completed
- Conditions
- Stroke
- Registration Number
- NCT02916030
- Lead Sponsor
- Assiut University
- Brief Summary
Stroke remains one of the most devastating neurological diseases, often causing death, or gross physical impairment. It is the second most common cause of death worldwide and a major cause of acquired disability in adults.Vitamin D deficiency has been reported to contribute to the risk of cardiovascular disease especially stroke.
- Detailed Description
This case -control observational prospective study will conducted on fifty patients with first -ever acute onset stroke within seven days (25 patients with hemorrhagic stroke and 25 patients with ischemic stroke )
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Onset is within one week
- Confirmed stroke by brain CAT and / or MRI scan either haemorrhage or infarction
Exclusion Criteria
- Cognitive and mental changes
- Recurrent stroke
- Hepatic and renal impairment
- Endocrinal diseases
- Steroid therapy
- Vitamin D or Ca supplementation
- Previous fractures
- Bone diseases
- brain neoplasm,
- Autoimmune diseases
- History of acute and chronic inflammatory diseases
- Malignancy,
- Trauma
- Surgery
- Acute vascular diseases that occurred within four weeks prior the onset of stroke
- History myocardial infarction ˂3 months.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method serum 25 (OH) D levels Within the first 24 hours serum 25 (OH) D levels
- Secondary Outcome Measures
Name Time Method Stroke subtypes Within the first 24 hours Stroke risk factors Within the first 24 hours Stroke severity Within the first 24 hours Stroke severity will be assessed by Scandinavian Stroke scale Stroke (SSS)
Stroke etiology Within the first 24 hours
Trial Locations
- Locations (1)
Faculty of Medicine
🇪🇬Assiut, Egypt
Faculty of Medicine🇪🇬Assiut, Egypt