ERAS in Elderly Colorectal Cancer Surgery

Completed

• Conditions: ERAS; Colo-rectal Cancer; Elderly (people Aged 65 or More); Minimally Invasive Surgery

• Registration Number: NCT06764888
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Enhanced recovery protocol consisted of a series of elements aiming to optimize and standardize perioperative care. This study aims to evaluate the safety and feasibility of a modified ERAS protocol following colorectal surgery in the elderly population, aged 65 years or older. This is a retrospective study based on prospectively collected data. Patient privacy has been carefully protected throughout the research process, and no aspect of this study interfered with or altered the patients' treatment or clinical care.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-06-05
• Status Verified: 2024-12
• Primary Completion: 2024-12-05
• Study Completion: 2024-12-05
• Study First Submitted: 2024-12-17
• Study First Submitted QC: 2025-01-07
• Last Update Submitted: 2025-01-07
• Study First Posted: 2025-01-09
• Last Update Posted: 2025-01-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1392

Inclusion Criteria

• they underwent radical resection for colorectal cancer
• the procedure was minimally invasive surgery
• they were aged 65 or older
• they provided signed informed consent.

Exclusion Criteria

• Patients who underwent emergency surgery for colorectal cancer.
• Patients with incomplete medical records or missing data relevant to the study.
• Patients with synchronous malignancies or a history of other cancers within the past five years.
• Patients with severe comorbidities (e.g., advanced cardiovascular, respiratory, or renal diseases) that contraindicate ERAS protocol implementation.
• Patients with preoperative metastatic disease or locally advanced tumors requiring palliative procedures.
• Patients who did not comply with or complete the ERAS protocol during the perioperative period.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Short-term postoperative complications rate.	3 months	Measurement outcomes included the rate of short-term postoperative complications, overall morbidity, early morbidity, reoperation rate, 30-day readmission rates and 30-day mortality rates. Postoperative complications were carefully recorded and classified using the Clavien-Dindo classification system for a standardised severity evaluation. These complications are critical for assessing surgical outcomes and ensuring patient safety. Early complications were defined as those occurring during the initial hospitalisation or within 30 days of surgery, while late complications were defined as those arising after the patient's discharge from the hospital.

Secondary Outcome Measures

Name	Time	Method
Days of Hospital Stay and Time to First Passage of Flatus	3 months	Measurement outcomes are the rate of post-operative recovery times, including postoperative stay(days) and first passage of flatus(days).

Trial Locations

Locations (1)

Chang Gung Memorial Hospital; 🇨🇳 Taoyuan City, Taiwan