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Clinical Trials/CTRI/2024/11/076645
CTRI/2024/11/076645
Not yet recruiting
Phase 3

A comparative evaluation of external oblique intercostal plane block and intrathecal morphine in patients undergoing open donor hepatectomy : A randomized control trial

Institute of Liver and Biliary Sciences Hospital1 site in 1 country60 target enrollmentStarted: November 20, 2024Last updated:

Overview

Phase
Phase 3
Status
Not yet recruiting
Sponsor
Institute of Liver and Biliary Sciences Hospital
Enrollment
60
Locations
1
Primary Endpoint
To compare the postoperative fentanyl consumption at 24 hours between the external oblique intercostal and intrathecal morphine groups

Overview

Brief Summary

Postoperative pain is an important cause of morbidity in voluntary healthy individuals undergoing donor hepatectomy. 

A single shot of Intrathecal Morphine is a simple, effective and easily performed neuraxial technique with low technical failure rate  .

Ultrasound guided External Oblique intercostal Plane block is an emerging technique and is easy to perform , reliable and an alternate to Intrathecal Morphine .

In this study , we aim to compare the Ultrasound Guided External Oblique Intercostal Block and Intrathecal Morphine for pain management in donor hepatectomy surgery .

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Age – 18 to 60 years undergoing open living donor hepatectomy.
  • Patients giving consent.

Exclusion Criteria

  • Patient refusal Contraindication to neuraxial anaesthesia Allergy to local anesthetics Allergy to morphine Insufficient comprehension to use of PCA.

Outcomes

Primary Outcomes

To compare the postoperative fentanyl consumption at 24 hours between the external oblique intercostal and intrathecal morphine groups

Time Frame: upto first 24h in the postoperative period

Secondary Outcomes

  • To compare the postoperative pain (both static and dynamic ) using NRS score in between the two groups(To compare the time of first rescue analgesia requirement in both the groups)

Investigators

Sponsor
Institute of Liver and Biliary Sciences Hospital
Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

Dr Manikandan G

INSTITUTE OF LIVER AND BILIARY SCIENCES

Study Sites (1)

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