ISRCTN67819491
Completed
未知
Myocardial perfusion and microvascular dysfunction in stable coronary artery disease during hyperoxaemia
niversity of Leeds (UK)0 sites90 target enrollmentAugust 14, 2014
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity of Leeds (UK)
- Enrollment
- 90
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Known coronary artery disease involving one or more major epicardial vessels (\=2\.5mm diameter) with severe coronary artery disease (coronary luminal stenosis severity \=70% or FFR \=0\.8\).
- •For the healthy volunteer group:
- •No known risk factors for underlying coronary artery disease
Exclusion Criteria
- •1\. Clinically unstable
- •2\. Previous coronary artery bypass grafting
- •3\. Contraindication to adenosine (regular adenosine antagonist medication, significant reversible airways disease, second or third degree atrioventricular heart block, sinoatrial disease)
- •4\. Pregnancy or breast feeding
- •5\. Recent acute coronary syndrome (\<6 weeks)
- •6\. Nonsinus rhythm
- •7\. Chronic obstructive airways disease with a history of hypercapnic respiratory failure
- •8\. Three vessel coronary artery disease
- •9\. Claustrophobia
- •10\. Known adverse reaction to adenosine or iodinated contrast agents
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Phase 1
Quantification of diseases in small vessels of the human myocardium - a new approach in quantificatioEUCTR2013-003234-32-DEniversitätsklinikum Münster125
Recruiting
Not Applicable
Microvascular Dysfunction in Acute Myocardial Infarction and its Relation to Outcome.NL-OMON35137Catharina-ziekenhuis25
Completed
Not Applicable
Analysis of Coronary Microvascular Dysfunction and Cardiac Function for Patients with Coronary Artery Disease Undergoing Elective Percutaneous Coronary InterventioJPRN-UMIN000010345Shinshu University School of Medicine200
Completed
Not Applicable
Association between coronary microvascular dysfunction and glycemic variabilityIschemic heart diseaseJPRN-UMIN000022404Chiba university Graduate School of Medicine40
Not yet recruiting
Phase 4
Myocardial perfusion and function in chronic heart failure patients treated with erythropoietin assessed by PET and MRIHeart failureImpaired cardiac function10019280NL-OMON33549Vrije Universiteit Medisch Centrum40