Skip to main content
Clinical Trials/ISRCTN67819491
ISRCTN67819491
Completed
未知

Myocardial perfusion and microvascular dysfunction in stable coronary artery disease during hyperoxaemia

niversity of Leeds (UK)0 sites90 target enrollmentAugust 14, 2014

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
niversity of Leeds (UK)
Enrollment
90
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 14, 2014
End Date
TBD
Last Updated
9 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Leeds (UK)

Eligibility Criteria

Inclusion Criteria

  • Known coronary artery disease involving one or more major epicardial vessels (\=2\.5mm diameter) with severe coronary artery disease (coronary luminal stenosis severity \=70% or FFR \=0\.8\).
  • For the healthy volunteer group:
  • No known risk factors for underlying coronary artery disease

Exclusion Criteria

  • 1\. Clinically unstable
  • 2\. Previous coronary artery bypass grafting
  • 3\. Contraindication to adenosine (regular adenosine antagonist medication, significant reversible airways disease, second or third degree atrioventricular heart block, sinoatrial disease)
  • 4\. Pregnancy or breast feeding
  • 5\. Recent acute coronary syndrome (\<6 weeks)
  • 6\. Nonsinus rhythm
  • 7\. Chronic obstructive airways disease with a history of hypercapnic respiratory failure
  • 8\. Three vessel coronary artery disease
  • 9\. Claustrophobia
  • 10\. Known adverse reaction to adenosine or iodinated contrast agents

Outcomes

Primary Outcomes

Not specified

Similar Trials