Myocardial perfusion and microvascular dysfunction in stable coronary artery disease during hyperoxaemia

niversity of Leeds (UK)0 个研究点目标入组 90 人开始时间: 2014年8月14日最近更新: 2016年10月17日

试验速览

暂无简介。

•Known coronary artery disease involving one or more major epicardial vessels (=2.5mm diameter) with severe coronary artery disease (coronary luminal stenosis severity =70% or FFR =0.8).
•For the healthy volunteer group:
•No known risk factors for underlying coronary artery disease

•1. Clinically unstable
•2. Previous coronary artery bypass grafting
•3. Contraindication to adenosine (regular adenosine antagonist medication, significant reversible airways disease, second or third degree atrioventricular heart block, sinoatrial disease)
•4. Pregnancy or breast feeding
•5. Recent acute coronary syndrome (<6 weeks)
•6. Nonsinus rhythm
•7. Chronic obstructive airways disease with a history of hypercapnic respiratory failure
•8. Three vessel coronary artery disease
•9. Claustrophobia
•10. Known adverse reaction to adenosine or iodinated contrast agents

发起方

niversity of Leeds (UK)