NCT07072572已完成3 期
Lung Point Of Care Ultrasond (L-Pocus)-Guided Administration Of Intravenous Albumin In Decompensated Cirrhosis: A Pilot, Open Label, Randomized Controlled Trial
Centro Medico Issemym1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2023年3月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- Overall mortality at 30 days
研究概览
简要总结
To guide the administration of intravenous albumin by lung ultrasound in decompensated cirrhosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Older than 18 years.
- •Decompensated cirrhosis
- •Indication for intravenous albumin use
排除标准
- •Development of variceal hemorrage before the administration of albumin, respiratory failure previous to albumin use, or the presence of hepatocellular carcinoma
研究组 & 干预措施
Lung ultrasound guided albumin administration group
Experimental
Lung ultrasound guided albumin administration group
干预措施: Lower albumin dosage (Drug)
结局指标
主要结局
Overall mortality at 30 days
时间窗: 30 days
Overall mortality at 30 days
次要结局
- Acute kidney injury(Every 24 hours, during hospitalization, (assesed up to 28 days))
- acute-on-chronic liver failure(During hospitailization, (assesed up to 28 days))
- Resolution of SBP(Day three of antibiotic treatment initiated for spontaneous bacterial peritonitis.)
- Respiratory failure(Every 24 hours, during hospitalization, (assesed up to 28 days))
- Development of variceal hemorrhage(During hospitailization, (assesed up to 28 days))
- Total hospitalization time(30 days)
研究者
Luis Alejandro Rosales Renteria
Principal investigator
Centro Medico Issemym
研究点 (1)
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