Bacterial Infections in Patients with Cirrhosis in Argentina
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 472
- 试验地点
- 1
- 主要终点
- To estimate the prevalence of infections caused by multi-resistant microorganisms in patients with cirrhosis
研究概览
简要总结
In recent years, there has been an increasing prevalence of bacterial infections caused by multiresistant and extremely resistant organisms in patients with cirrhosis. These infections are associated with a worse prognosis, generate difficulties in the management of the patient during hospitalization and increase health costs.
The main objective of this project is to estimate the prevalence of infections by multiresistant bacteria in patients with cirrhosis. Additionally, the prevalence of other antibiotic resistance patterns and morbi-mortality in the study population will be evaluated.
For these purposes, a multicenter prospective cohort study will be carried out, including patients with cirrhosis who present bacterial infections at the time of admission, or during hospitalization.
Performing a study in Argentina on the clinical and microbiological characteristics of bacterial infections in patients with cirrhosis could be very useful to develop new strategies for prevention and treatment of this severe complication.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with cirrhosis
- •Patients older than 17 years.
- •Patients who are hospitalized for bacterial infections, or who develop bacterial infections while hospitalized
排除标准
- •Refusal to participate in the informed consent process
结局指标
主要结局
To estimate the prevalence of infections caused by multi-resistant microorganisms in patients with cirrhosis
时间窗: at the moment of the diagnosis of the bacerial infection
次要结局
- To evaluate variables associated with infections caused by multi-resistant microorganisms in patients with cirrhosis(at the moment of the diagnosis of the bacerial infection)
- To evaluate the effect of infections caused by multi-resistant microorganisms on the in-hospital survival of patients with cirrhosis(30 days)
研究者
SEBASTIAN MARCIANO
Assistant Professor of Hepatology , Principal Investigator
Hospital Italiano de Buenos Aires