Effects of a standardised herbal formula Wei Nao Kang(WNK) on neurocognitive function in healthy volunteers: a pilot study

Phase 2

Recruiting

• Conditions: eurocognitive function in healthy individuals; Neurocognitive function in healthy individuals; Alternative and Complementary Medicine - Herbal remedies; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12610000947000
• Lead Sponsor: niversity of Western Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-11-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

Age 22 to 75 years old
-Non-smoker
-Body weight not more than 15% of the ideal weight range for the subject’s height and frame (< 25 kg/m2) as in Ciba Geigy tables
-Mini Mental State Exam (MMSE) score of 21 or greater

Exclusion Criteria

-Pregnant women
-History of allergies
-Serious gastrointestinal disorders such as peptic ulcers
-History of asthma, bronchitis, or other serious pulmonary disorders
-History of drug or alcohol abuse
-Use of medication (in particular anti-coagulants and cognitive enhancers), participation in a clinical trial for an experimental drug, or blood donation within the last 30 days before the study
-Diabetes
-Diagnosed psychiatric disorders
-Use of any cognitive enhancing substances, either herbal or pharmaceutical
-Any significant abnormality, on laboratory tests including full blood count, liver, and renal test, as judged by a medically trained professional
-Any other condition judged by the physician that would place the volunteer in a risk category for the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive performance; simple reaction time, word recall, face recall, picture recall, spatial working memory, sustained attention which form part of the Compass test battery.[Baseline<br>Posttreatment (at 1 week)]

Secondary Outcome Measures

Name	Time	Method
Cardiovascular function (pulse pressure and augmentation index)[Baseline<br>Posttreatment (1 week)];Electroencephalogram (P300)[Baseline<br>Posttreatment (1 week)]