Rapid Intervention with GTN in Hypertensive stroke Trial (RIGHT). Determining the potential of ambulance-based randomised controlled trials in patients with hyperacute stroke; assessment of glyceryl trinitrate in lowering blood pressure. - RIGHT

Phase 1

• Conditions: Hypertension in acute stroke; MedDRA version: 9.1 Level: LLT Classification code 10020772 Term: Hypertension

• Registration Number: EUCTR2007-004766-40-GB
• Lead Sponsor: niversity of Nottingham

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-02-01
• Study Completion: 2012-07-13
• Last Update Posted: 28 February 2019

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

• Adult patients; >40 years of age • Paramedic assessment of stroke on basis of positive ‘Face & Arm weakness & Speech abnormality Test (FAST) in the context of a call to a patient with a ‘possible acute stroke’; • Event <4 hours of onset (sleep stroke - onset as bed time); • High systolic BP (>140 mmHg).
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

• No consent/assent is available • GTN is indicated (e.g. concurrent angina) • GTN is contraindicated (e.g. dehydration, hypovolaemia); • Age <40 years;30 • Coma; GCS =8 • History of seizures30 • Non-ambulatory pre-morbidly (modified Rankin scale of >2)30 • Hypoglycaemia (if glucose tested). • Patients from a nursing home

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified