Pilot study on Idiopathic intracranial Hypertension: Evaluation of pupillometry as a clinical follow-up parameter
- Conditions
- G93.2Benign intracranial hypertension
- Registration Number
- DRKS00017815
- Lead Sponsor
- Charité Campus Virchow-KlinikumKlinik für Neurologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion criteria for patients: 1. patient is able to give informed consent and gives informed consent. 2. Signed informed consent. 3. Age from 18 to 70 years. 4. Diagnostic of idiopathic intracranial hypertension according to Friedman-criteria (Friedman et. al. 2013). 5. Planned lumbar puncture with measuring of the opening pressure. Inclusion criteria for healthy controls: 1. patient is able to give informed consent and gives informed consent. 2. Signed informed consent. 3. Age from 18 to 70 years. 4. no neurological or ophthalmological disease.
Exclusion criteria for patients: 1. non-corrected refractory anomalies >2,5 dpt res. <-2,5 dpt. 2. Other neuroophthalmological diseases influencing the pupillary light reflex. Exclusion criteria for healthy controls: 1. non-corrected refractory anomalies >2,5 dpt res. <-2,5 dpt. 2. Other neuroophthalmological diseases influencing the pupillary light reflex.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Investigation of the pupillary light reflex in patients with idiopathic intracranial hypertension compared to healthy controls
- Secondary Outcome Measures
Name Time Method Investigation of the pupillary light reflex during the course of disease and in relation to clinical measures and findings in the clinical routine. Specifically the relation with the liquor opening pressure and with sonography of the orbita and the brain venes shall be investigated. In addition, quality of life and headache intensity will be measured longitudinally.