A study to determine the frequency of occurance of migraine associated vertigo and to assess its response to treatment with flunarizine

Completed

• Conditions: Patients with migrainous vertigo

• Registration Number: CTRI/2012/07/002779
• Lead Sponsor: Dr Anjali Lepcha

Brief Summary

This is an open-labeled, blocked, randomized trial with two treatment arms. Patients suffering from migraine related vertigo visiting the specialised audiovestibular clinic in CMC hospital are evaluated using a specific questionnaire regarding the patients’ symptoms, past treatment, co-morbidities and family history, followed by a complete clinical examination and audiovestibular tests and appropriate radiological investigations. All patients who qualify for the study are entered serially into a register and  block randomized into two treatment arms, with one arm receiving specific migraine directed treatment (flunarizine) and another arm receiving general vertigo treatment. All patients are followed up for six months. The follow is done by a questionnaire that addresses symptom relief, increase or decrease in severity of symptoms and the data is analysed for differences in response to treatment between the two groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08-31
• Last Update Posted: 2012-06-14

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Patients with migrainous vertigo.

Exclusion Criteria

• Any patients with typical history of BPPV (and + Hallpikes test) Any patients with typical Meniere’s disease (AAOC criteria 1995) Any patient with past history of chronic discharging ears/history of surgery to ear/ history of permanent hearing loss.
• Other neurological disorders i.e. stroke, intracranial tumours Any patient who is receiving a calcium channel blocker for hypertension.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in the frequency, severity and duration of vertigo and headaches	On follow-up after 6 months of treatment

Trial Locations

Locations (1)

Audiovestibular unit; 🇮🇳 Vellore, TAMIL NADU, India

Audiovestibular unit

🇮🇳Vellore, TAMIL NADU, India

Dr Anjali Lepcha

Principal investigator

04162286075

anjalilepcha@yahoo.com