Effects of aprepitant (Emend ®) on the pharmacokinetics of fentanyl.

Recruiting

• Conditions: cancer; pain; 10027656

• Registration Number: NL-OMON38557
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 14

Inclusion Criteria

age >= 18
stable use of fentanyl patch
written informed consent

Exclusion Criteria

using fentanyl as rescue medication
intolerance for aprepitant

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>AUC, clearance</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>pain score (according Numerical Rating Scale)<br /><br>side effects (according CTC toxicity criteria)</p><br>