Effect of a controlled release system of doxycycline for control of periodontal disease: randomized double masking clinical trial

niversidade Federal de Minas Gerais0 个研究点开始时间: 2017年10月23日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Individuals presenting chronic periodontitis (AAP-1999); individuals with contralateral quadrants containing at least one molar with presence of sites with probing depth 5 mm, clinical insertion level 6 mm and bleeding at probing; over 18 years.

•Presence of periapical and pulpal alterations; presence of gingivitis and acute periodontal conditions (abscesses and acute necrotizing periodontitis); presence of candidosis and changes in the mucosa; allergy to the components of gels and periodontal dressings; presence of systemic diseases (cardiovascular, blood dyscrasias, immunodeficiencies, transplanted, diabetes, osteoporosis, nephropathies, hepatopathies); need for antibiotic prophylaxis before periodontal treatment; use of systemic antibiotics, chemotherapeutics of controlled or continuous use and others that may interfere with the inflammatory process or have adverse effects directly in the periodontium in the last 6 months; pregnancy and contraceptive users during the study and during the previous three months or lactation; smokers; surgical or non-surgical periodontal treatment in the last 6 months; treatment with chlorhexidine mouthwash 0.12% or other topical chemical agent in the last 6 months.

发起方

niversidade Federal de Minas Gerais