Better targeting of antidepressants in older people: the influence of age and genetic background on serotonin signalling - Better targeting of Antidepressants 2

• Conditions: Depression; MedDRA version: 12.0Level: LLTClassification code 10021036Term: Hyponatraemia; MedDRA version: 12.0Level: LLTClassification code 10017955Term: Gastrointestinal haemorrhage; MedDRA version: 12.0Level: LLTClassification code 10040108Term: Serotonin syndrome

• Registration Number: EUCTR2009-016716-20-GB
• Lead Sponsor: Brighton and Sussex University Hospitals NHS Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-03-17
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Patients will be recruited through the Care of the Elderly wards and outpatients at the Brighton and Sussex University Hospitals Trust. All patients will be 80 years or older and able to consent to take part in the study or approval to take part in the study will be obtained from an appropriate consultee. A new diagnosis of depression, to be initiated on first line treatment with serotonin re-uptake inhibitors.
Are the trial subjects under 18?
Number of subjects for this age range:
F.1.2 Adults (18-64 years)
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Patients will be excluded if they are already undergoing treatment for depression with SSRIs or other therapeutic agents. Patients less than 80 years of age will also be excluded.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified