Improving parenchymal phase imaging of the pancreas with multidetector CT using experience from dynamic contrast enhanced MR studies.

Completed

• Conditions: Cancer: Pancreatic; Cancer; Pancreatic

• Registration Number: ISRCTN84780767
• Lead Sponsor: Record Provided by the NHSTCT Register - 2006 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-09-29
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Age over 18 - pancreatic adenocarcinoma is unusual below this age and children are more sensitive to additional ionising radiation than adults
2. Stage III ovarian cancer or colorectal cancer
3. Routine attendance for contrast enhanced abdominal CT - no patients not otherwise having CT and contrast will be approached.

Exclusion Criteria

1. Severe local disease affecting pancreatic aorta/branches. This may introduce delays to the arrival of contrast due to compromise of arteries (SMA/Coeliac axis)
2. Major atherosclerotic disease of SMA/Coeliac axis - again, to avoid significant delay in contrast path distal to pancreatic aorta
3. Significant pancreatic resection - absence of normal pancreatic tissue will preclude our numerical assessment of enhancement
4. Pre-existing pancreatic disease - cancer or pancreatitis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified