Functional magnetic resonance imaging of pancreatic cancer: a feasibility and reproducibility study

Completed

• Conditions: pancreatic cancer; 10019815

• Registration Number: NL-OMON41555
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

* Patients with pancreatic tumors, with histological or cytological proof of adenocarcinoma or a high suspicion on CT imaging.
* Any tumor with a size * 1cm
* WHO-performance score 0-2
* Written informed consent

Exclusion Criteria

* Any psychological, familial, sociological or geographical condition potentially hampering adequate informed consent or compliance with the study protocol.
* Contra-indications for MR scanning, including patients with a pacemaker, cochlear implant or neurostimulator; patients with non-MR compatible metallic implants in their eye, spine, thorax or abdomen; or an aneurysm clip in their brain; patients with severe claustrophobia.
* Renal failure (GFR < 60 ml/min) hampering safe administration of a double bolus of Gadolinium containing MR contrast agent.
* For the reproducibility part of the protocol: surgery, radiation and/or chemotherapy foreseen within the timeframe needed for MRI scanning.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Reproducibility of MRI parameters.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correlation of MRI parameters with histology.</p><br>