Oculomotor Deficits in Parkinson's Disease: Enhancing Eye Movement Performance and Dynamic Visual Acuity With Oculomotor Training Using a Pilot Randomized Clinical Trial Design
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- The Hong Kong Polytechnic University
- Enrollment
- 27
- Locations
- 1
- Primary Endpoint
- Smooth Vergence eye movements
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Parkinson's disease (PD) is a common neurodegenerative disorder which is characterized by both motor and non-motor symptoms and usually affects people aged 50 years or above. Many studies showed eye movement deficits and visual changes in patients with PD.
Previous studies have also indicated that clinical eye movement training could enhance the functional performance of patients with various eye movement problems resulting from ocular and neurodegenerative diseases.
In this study, we will investigate the effectiveness of eye movement training on dynamic vision and functional performance in PD patients with oculomotor deficits.
Investigators
Allen MY Cheong
Associate Professor
The Hong Kong Polytechnic University
Eligibility Criteria
Inclusion Criteria
- •Parkinson's Disease diagnosed by a neurologist or geriatrician with the range of Stage
- •1 to 4 (Hoehn and Yahr Classification)
- •Able to speak and comprehend Cantonese dialect
- •Able to travel independently
Exclusion Criteria
- •Any congenital eye problem (e.g. congenital strabismus or amblyopia in either eye) or any manifest eye diseases (e.g. macular degeneration, glaucoma, etc)
- •Severe medical problems (e.g. stroke)
- •Cognitive impairment (e.g. dementia)
- •Presence of any psychiatric or neurological diseases (apart from Parkinson's disease) or receiving of any psychoactive pharmacological treatment
- •Receiving any medication that is known to affect eye movement and cognitive function
- •Previous formal vision rehabilitation or oculomotor intervention
Outcomes
Primary Outcomes
Smooth Vergence eye movements
Time Frame: Change from baseline at week 4 and change from baseline at week 12
Smooth vergence eye movement is measured using a head-mounted eye tracking while fixating at an approaching target moving at different speeds
Secondary Outcomes
- Sentence reading performance(Change from baseline at week 4 and change from baseline at week 12)
- Oculomotor characteristics(Change from baseline at week 4 and change from baseline at week 12)
- Passage reading performance(Change from baseline at week 4 and change from baseline at week 12)