Prevalence and Serotype Distribution of Streptococcus Pneumoniae in Healthy Vietnamese Children From 6 Months to 5 Years Old
- Conditions
- Streptococcus Pneumonia
- Registration Number
- NCT06638333
- Lead Sponsor
- Tam Anh Research Institute
- Brief Summary
This observational study is designed as a cross-sectional survey of children from 6 months and 5 years old who visit the Vietnam Vaccination Center (VNVC) system in Hanoi, Danang and Ho Chi Minh City for vaccination services.
After getting the informed consent form from a parent/guardian for their child(s) to participate in the study, nasopharyngeal swab sample will be taken. His/her guardian will be interviewed face-to-face with information related to epidemiological characteristics, nutritional status, child's birth history, hospitalization history, vaccination history, recent antibiotic usage, breastfeeding time, and environmental and lifestyle factors.
The goal is to document the burden and risk factors of pneumococcal infections in the community of healthy Vietnamese children. The main questions it aims to answer are:
* What is the prevalence of pneumococcus in healthy children?
* What is the distribution of pneumococcus serotypes in the community of healthy Vietnamese children?
* What are risk factors of pneumococcus infection in the community of healthy Vietnamese children?
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 800
- Children between 6 months and 5 years
- Children with chronic diseases (including immunologic diseases, neoplastic disorders, renal, cardiac, hepatic, or hematologic diseases, broncho dysplasia, Down syndrome, chronic otitis media with effusion)
- Children with acute/chronic upper or lower respiratory tract infection
- Children have used antibiotics within 1 week prior to entering the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of pneumococcal carriage in the nasopharynx in children from 6 months to 5 years old in the Vietnamese community Day 0 after recruitment Pneumococcal prevalence in children by age group, sex and geographical area
Serotype distribution of pneumococcal strains in Vietnamese children from 6 months to 5 years old in the community Day 0 after recruitment The number of carrier individuals by serotype will be determined for age group, sex and geographical area
- Secondary Outcome Measures
Name Time Method Risk factors associated with pneumococcal carriage Day 0 after recruitment Gender, age, urban vs rural setting, environmental, lifestyle factors and other factors will be analyzed.
Trial Locations
- Locations (3)
VNVC Da Nang
🇻🇳Da Nang, Vietnam
VNVC Icon4 Cau Giay
🇻🇳Hanoi, Vietnam
VNVC Tan Phu
🇻🇳Ho Chi Minh City, Vietnam