Geriatric Recovery Using Inpatient and Post-hospitalization Supplementation
- Conditions
- Aging
- Registration Number
- NCT03904615
- Brief Summary
The purpose of the study is to determine the feasibility of nutritional interventions designed to help older patients maintain physical function after being in the hospital. We will test the feasibility and effect of nutritional interventions with whey protein, collagen or placebo on functional recovery from hospitalization in community dwelling older adults.
- Detailed Description
We will compare in a randomized parallel design double blind pilot phase I study the feasibility of whey protein vs. collagen vs. isocaloric placebo supplementation in older adults during an acute hospitalization for a medical condition, and the treatments' effect size on physical function after hospital discharge.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 116
- Aged 65 years or older.
- Admitted to UTMB hospital for any acute medical condition
- English speaking
- Inability to consent
- Bed or wheelchair bound prior to hospitalization
- Estimated creatinine clearance 20 ml/min or less, or end stage renal disease not on dialysis
- AST/ALT 2.5 times above the normal limit
- Active cancer
- Palliative care/Hospice
- Estimated protein intake >1.2 g/kg/day during the previous 24 hours
- Any other condition or event considered exclusionary by the PI and faculty physician
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Physical Function Change from baseline to 30 days after discharge Short Physical Performance Battery (SPPB) scale, 0-12 points. 0=disabled; 12=high performance
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
UTMB Acute Care for Elders Unit
🇺🇸Galveston, Texas, United States
Jennie Sealy Hospital
🇺🇸Galveston, Texas, United States
UTMB Acute Care for Elders Unit🇺🇸Galveston, Texas, United States