Measuring HIV-related mortality during surveys in Africa

Not Applicable

Completed

• Conditions: HIV status of deceased sibling; Infections and Infestations; Human immunodeficiency virus [HIV] disease

• Registration Number: ISRCTN15197669
• Lead Sponsor: ational Institute of Allergy and Infectious Diseases (NIAID)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-10-12
• Study Completion: 2019-05-31
• Last Update Posted: 24 November 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 535

Inclusion Criteria

1. Aged 15-59 years old at the time of the study
2. Residing in the Karonga Health and Demographic Surveillance System (HDSS) area

Exclusion Criteria

1. Younger than 15 years old at the time of enrollment
2. Older than 59 years old at the time of enrollment
6. Not residing in the Karonga Health and Demographic Surveillance System (HDSS) area

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Sensitivity in recording the HIV status of deceased siblings in the ACASI and face-to-face groups. Sensitivity is defined as the proportion of HIV positive deaths according to KHDSS that were correctly reported as such by survey respondents.<br> 2. Specificity in recording the HIV status of deceased siblings in the ACASI and face-to-face groups. Specificity is defined as the proportion of HIV-negative deaths according to KHDSS that were correctly reported as such by survey respondents.<br> There will be one planned study visit per participant, with no planned follow-up. As such the outcomes will be measured at the one study visit. The trialists will measure the level of agreement between survey data and KHDSS data using Cohen’s Kappa in each study arm.<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. The sensitivity/specificity of the survey in recording the respondent's own HIV status<br> 2. The amount of time spent answering HIV-related questions, as measured internally by ODK<br> 3. The accuracy of the enhanced questionnaire in assessing the engagement of deceased siblings identified as HIV-infected on the HIV care cascade<br> There will be one planned study visit per participant, with no planned follow-up. As such the outcomes will be measured at the one study visit.<br>