Cellular Immune responses to Hepatitis B Virus (HBV)- Longitudinal follow up and Natural History

Not Applicable

Completed

• Conditions: Hepatitis B infection and Hepatitis B/HIV co-infection; Infection - Acquired immune deficiency syndrome (AIDS / HIV); Inflammatory and Immune System - Liver

• Registration Number: ACTRN12605000553673
• Lead Sponsor: IH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-09-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 104

Inclusion Criteria

There are two groups of patients in this study. Group A mono-infected with Hepatitis B, and those with co-infection HBV/HIV.Group A inclusion criteria: (also split into 6 recruiting groups)1- Acute hepatitis B2- Chronic hepatitis B, HBV DNA+ve , normal ALT , HBeAg +ve3- Chronic hepatitis B, HBV DNA +ve , normal ALT, HBeAg -ve4- Chronic hepatitis , HBV DNA +ve, increased ALT, no HBV treatment B, HBeAg +ve5- Chronic hepatitis B, HBV DNA +ve , increased ALT, no HBV treatment B, HBeAg -ve6- Chronic hepatitis B, undergoing 'flare' of hepatitis. Group B inclusion criteria:to be HIV/HBV co-infected.

Exclusion Criteria

No exclusion criteria

Study & Design

• Study Type: Observational
• Study Design: Not specified