Effectiveness of a pharmacist-driven intervention in chronic obstructive pulmonary disease
Not Applicable
- Conditions
- Chronic obstructive pulmonary diseaseRespiratoryChronic obstructive pulmonary disease, unspecified
- Registration Number
- ISRCTN78138190
- Lead Sponsor
- Memorial University of Newfoundland (Canada)
- Brief Summary
2016 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/27737686
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Stopped
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
1. Physician-diagnosed COPD
2. Age =40 years at trial enrollment
3. Sufficient ability to answer questionnaires in English
Exclusion Criteria
1. A known Forced Expiratory Volume in 1 second (FEV1)/ Forced Vital Capacity (FVC) of <30%
2. A diagnosis of dementia or a prescription for cholinesterase inhibitors
3. A terminal illness
4. Physician-diagnosed asthma
5. Participation in another clinical trial
6. If they do not provide consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change from baseline to 6 months in medication adherence using the medication possession ratio (MPR) and the Morisky Medication Adherence Scale (MMAS-8)
- Secondary Outcome Measures
Name Time Method <br> 1. Proportion of patients with a clinically significant change in adherence<br> 2. Proportion of patients defined as having ‘good adherence’<br> 3. Mean MPR between groups<br> 4. Quality of life as measured by the St. George’s Respiratory Questionnaire<br> 5. Medication inhalation technique using a pharmacist-scored checklist<br> 6. Healthcare resource utilization<br> 7. Antibiotic and oral corticosteroid use for COPD exacerbations<br> Measured at baseline and 6 months.<br>