To see the effect of differant doses of atracurium in relation to the surgical conditions in paediatric cataract surgery
- Conditions
- Health Condition 1: null- Patient posted for routine paediatric cataract surgery
- Registration Number
- CTRI/2014/05/004604
- Lead Sponsor
- Department of Anaesthesiology All India Institute of Medical Sciences New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 160
This prospective, double blind, randomized controlled trial would be conducted in the Department of Anesthesiology AIIMS, New Delhi after Institute Ethical Committee approval. Patients will than be divided into four groups:
In the operating room, standard monitors [electrocardiography (ECG), NIBP, pulse oximetry (SpO2)] will be applied. General anaesthesia will be induced with sevoflurane and oxygen till the loss of eyelash reflex. An intravenous line will be secured followed by injection fentanyl 1µg/kg. An anesthesiologist will then open the envelope to randomize patients into four groups.
Group I: Surgery without muscle relaxant
Group II: Will receive Atracurium at 25% ED95
Group III: Will receive Atracurium at 50%ED95
Group IV: Will receive Atracurium of 100%ED95
1.Child with major systemic illness
2.Active upper respiratory tract infection
3.Refusal to participate in the study
4.ASA III and IV
5.Refusal to participate in the study
6.Any neuromuscular disease
7.Children with craniofacial anomalies.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To see whether muscle relaxant is required or not in paediatric cataract surgery <br/ ><br>2.To see the minimum dose of muscle relaxant necessary for cataract surgery. <br/ ><br>Timepoint: From time of starting inhalation agents till the extubation of LMA.
- Secondary Outcome Measures
Name Time Method To see the minimum dose of Atracurium required for paediatric cataract surgeryTimepoint: Induction of anaesthesia to till shifting of patient to recovery room.