Comparison of effectiveness of two different doses of Atracurium which is used for muscle relaxation in emergency intubations for emergency laparotomy surgeries.
Not Applicable
Completed
- Conditions
- Health Condition 1: K566- Other and unspecified intestinal obstruction
- Registration Number
- CTRI/2020/07/026582
- Lead Sponsor
- HSK HOSPITALnavanagarbagalkot
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1.Patient posted for emergency laporotomy surgeries under General anaesthesia
2.Patient belongs to ASA physical status 2 or 3
3.Patient with Age 20 ââ?¬â?? 65 years.
Exclusion Criteria
1.patients with history of severe cardiac disease.
2.patients with history of metabolic or neuromuscular disorders.
3.predicted difficult airway patients.
4.patients with history of interacting drug /drug allergy
5.Patients refusal to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -To compare two different doses of atracurium and its efficacy using NM monitoring for intubation conditions. <br/ ><br>Timepoint: -Grading of intubating conditions after induction and neuro muscular monitoring (TOF) will be done till the spontaenous efforts of breathing. NMT will be monitored every 12 seconds from the onset of the induction of anesthesia until measurements reaches zero. After that, every ten minutes until TOF counts two twitches indicating the spontaneous recovery time from Atracurium action.
- Secondary Outcome Measures
Name Time Method -To compare Hemodynamic responses (SBP, DBP and HR) during and after intubation.Timepoint: -Hemodynamic responses (SBP, DBP and HR) will be assessed before and after intubation. These parameters will be measured every minute for first ten minutes and then every ten minutes until TOF counts two twitches indicating the spontaneous recovery from Atracurium action.