Insulin sensitivity in appropriate for gestational age and small for gestational age term and preterm infants - Insulin sensitivity in AGA and SGA term and preterm infants.

Academisch Medisch Centrum0 个研究点目标入组 80 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•- Need for blood sampling on a clinical indication, e.g. for neonatal screening program or before discharge home.
•- (Near) term age at the moment of blood sampling (corrected postconceptional age 36-42 weeks)
•- Full oral or enteral nutrition (>120 ml/kg/day)

•- Uncertain gestational age
•- Supplementary intravenous nutrition (parenteral nutrition or glucose infusion)
•- Disturbances in glucose metabolism (hypo- or hyperglycemia at a normal carbohydrate intake, or need for insulin therapy to maintain glucose concentration between 2.6 and 8 mmol/l)
•- Need for medication interfering with glucose metabolism (vasopressors, corticosteroids)
•- Positive family history of type 2 diabetes in first degree relatives
•- Perinatal asphyxia (5 minute Apgar score <7)
•- Current infection (clinical or laboratory evidence: lethargy or irritability, hypo- or hyperthermia, temperature instability, tachypnea, apnea, bradycardia, hypotension, gastric retention, abdominal distension, pallor, elevated CRP-level, leukocytosis or leukocytopenia and increased number of band neutrophils)
•- No informed consent from parents or legal guardians

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