Evaluating the effectiveness of ketamine on muscle pain (myalgia), headache and restlessness (agitation) after electroconvulsive therapy in patients with major depression disorder.

Not Applicable

Conditions: Electroconvoulsive therapy induced myalgia.
Myalgia

Registration Number: IRCT138904221766N4

Lead Sponsor: Kurdistan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 50

Inclusion Criteria

Major depression based on DSM 4 criteria, physical condition in accordance with ASA Class 1 or 2, ability and capacity to sign informed consent sheet.
Exclusion criteria: history of major systemic disease, history of neuromuscular disease, history of myalgia.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Myalgia. Timepoint: At 6, 12, 24 and 48 hours after ECT. Method of measurement: Myalgia graded as follow: absence of myalgia = no; stiffness or muscle pain did not need treatment = mild; muscle pain or stiffness reported spontaneously by the patient, and required therapy = moderate; very severe discomfort = severe.;Headache. Timepoint: In the first 24 hours after ECT. Method of measurement: Visual Analoge Scale.;Agitation. Timepoint: In the recovery period. Method of measurement: 1. Yes: motor restlessness, severe motor movement, and besides, un-aimed try to leave the bed, wanting to get up from bed, high loud crying, pulling catheters, confusion and poor response to verbal commands) 2 . No: not mentioned in any of the above scenarios.

Secondary Outcome Measures

Name	Time	Method
Seizure duration. Timepoint: After induction of ECT. Method of measurement: Second.;Mean arteial blood preasure. Timepoint: Befor induction of anesthesia ,after induction of anesthesia ,and after termination of seizure. Method of measurement: Milimeter of Hg.;Heart Rate. Timepoint: Befor induction of anesthesia , after induction of anesthesia ,and after termination of seizure. Method of measurement: Beat /minute.