Study of Effects of native renal Artery denervation in Post TRANSPLANT Hypertension: a non-randomised unblinded interventional study

HS Greater Glasgow and Clyde (UK)0 个研究点目标入组 20 人开始时间: 2013年5月9日最近更新: 2015年1月13日

试验速览

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•1. Patients aged 18?85 years, either sex, with a clinic systolic blood pressure of 140 mmHg or more, despite compliance with two or more antihypertensive drugs, are eligible for inclusion
•2. Patients should be >12 months post renal transplantation with no evidence of rejection in past 3 months and doses of immunosuppression should be stable for >6 weeks prior to study entry

•1. Inability to give informed consent
•2. Contraindications to MRI imaging (pacemaker, extreme claustrophobia)
•3. Pregnancy and breastfeeding
•4. Impaired transplant kidney function (estimated glomerular filtration rate [GFR] <30 ml/min)
•5. Known secondary cause of hypertension other than renal disease (e.g. Conn's syndrome, Phaeochromocytoma etc)

发起方

HS Greater Glasgow and Clyde (UK)