A study to explore whether pulmonary rehabilitation in Uganda for adults with chronic respiratory disease is practical and acceptable to patients

Not Applicable

Completed

• Conditions: Chronic Lung Disease; Respiratory

• Registration Number: ISRCTN14312425
• Lead Sponsor: Plymouth University, Peninsula Schools of Medicine and Dentistry

Brief Summary

2017 Results article in https://pubmed.ncbi.nlm.nih.gov/29270007/ (added 07/11/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-21
• Study Completion: 2016-03-01
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

1. Aged 18 years or over
2. Diagnosis of chronic obstructive pulmonary disease (COPD) or tuberculosis (TB)
3. Seen at Mulago Hospital as an inpatient or outpatient
4. Medical Research Council dyspnoea score grade 2 (MRC2) or higher
5. No unstable cardiovascular disease or locomotor difficulties that preclude exercise

Exclusion Criteria

1. Smear positive TB for those with previous TB treatment
2. Unwilling or unable to attend a PR programme
3. Unable to provide informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> The feasibility and acceptability of pulmonary rehabilitation programme is determined at baseline, 6 weeks (end of intervention) and 12 weeks (6 weeks after intervention completion) using the following measures:<br> 1. Walking distance measured using the Incremental Shuttle Walking Test<br> 2. Quality of life measured using the disease specific Clinical COPD and EQ-5D questionnaires<br> 3. Breathlessness measured using the MRC Dyspnoea Scale, Spirometry, Oximetry and Biometrics<br> 4. Functional ability measured using the Karnofsky Scale, Borg Score and sit to stand time<br> 5. Participant experience measured using ethnographic observations, individual interviews and focus groups at baseline, during the pulmonary rehabilitation intervention and 12 weeks (6 weeks after intervention completion)<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Chest pain is measured using a subset of questions from the Brief Pain Inventory at baseline, 6 weeks (end of intervention) and 12 weeks (6 weeks after intervention completion)<br> 2. Haemoptysis is measured using a single question rating scale at baseline, 6 weeks (end of intervention) and 12 weeks (6 weeks after intervention completion)<br> 3. Depression is measured using the PHQ-9 all measured at baseline, 6 weeks (end of intervention) and 12 weeks (6 weeks after intervention completion)<br>