Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Adrenalectomy

Not Applicable

Terminated

• Conditions: Pain Management; Nerve Block; Laparoscopic Adrenalectomy
• Interventions: Procedure: single-injection QLB(quadratus lumborum block); Procedure: Placebo control

• Registration Number: NCT03844477
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

This prospective, randomized ,control study aims to compare the analgesic effect,quality of recovery, length of hospital stay ,et al. between single-injection QLB(quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-02-15
• Study First Submitted QC: 2019-02-15
• Study Start: 2019-02-16
• Study First Posted: 2019-02-18
• Primary Completion: 2019-05-01
• Study Completion: 2019-05-15
• Status Verified: 2019-09
• Last Update Submitted: 2019-09-02
• Last Update Posted: 2019-09-04

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Age 18-70 yrs
• American Society of Anesthesiologists physical statusⅠ-Ⅲ
• Undergo laparoscopic adrenalectomy
• Informed consent

Exclusion Criteria

• A known allergy to the drugs being used
• Coagulopathy, on anticoagulants
• Analgesics intake, history of substance abuse
• Participating in the investigation of another experimental agent
• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
single-injection QLB(quadratus lumborum block)	single-injection QLB(quadratus lumborum block)	Single-injection of QLB with local anesthetic is given preoperatively
Placebo control	Placebo control	Single-injection of QLB with NS is given preoperatively

Primary Outcome Measures

Name	Time	Method
pain numeric rating scale (NRS, 0-10)pain score at activity at 12 hours after surgery	At 12hours after the surgery

Secondary Outcome Measures

Name	Time	Method
The pain scores at rest determined by the numeric rating scale (NRS, 0-10)	At 2,4, 8, 12,24 ,48,72hours after the surgery
patient's satisfaction with anesthesia and analgesia	48 hours after surgery	use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia and analgesia
ambulation time	within5 days after surgery
incidence of postoperative nausea and vomiting (PONV)	within 24 postoperative hours
time of restart anal exhaust	within 5 days after surgery
Postoperative length of hospital stay	up to2 weeks after surgery
The pain scores at activity determined by the numeric rating scale (NRS, 0-10)	At 2,4, 8, 24 ,48,72hours after the surgery

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, China