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临床试验/NCT01379664
NCT01379664已完成不适用

Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project

The Cleveland Clinic1 个研究点 分布在 1 个国家目标入组 1,584 人开始时间: 2011年7月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
1,584
试验地点
1
主要终点
Hospital Length of Stay

研究概览

简要总结

Preliminary retrospective data suggest that the relatively soluble but inexpensive volatile anesthesia isoflurane prolongs the duration of hospitalization compared to the less soluble but more expensive anesthetic sevoflurane. Even a small reduction in the duration of hospitalization would easily compensate for the modest additional cost of sevoflurane. The investigators therefore propose to test the primary hypothesis that duration of hospitalization is longer with isoflurane than sevoflurane.

The investigators will also test the secondary hypotheses that: 1) pain scores are greater in patients recovering from isoflurane than sevoflurane anesthesia; and, 2) opioid consumption is greater after isoflurane than sevoflurane anesthesia. All statistical analyses will be adjusted for age, gender, race, baseline risk, 9 and procedure.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Must have surgery in G operating room suite

排除标准

  • 未提供

研究组 & 干预措施

Isoflurane

Experimental

Isoflurane is to be administered to patients in this arm during surgery

干预措施: Isoflurane (Drug)

Sevoflurane

Experimental

Sevoflurane is to be administered to patients in this arm during surgery

干预措施: Sevoflurane (Drug)

结局指标

主要结局

Hospital Length of Stay

时间窗: participants will be followed for the duration of hospital stay, an expected average of 3 days

次要结局

  • Time-weighted Average Verbal Rating Pain Score(up to 72 hours after surgery)
  • Total Intraoperative Opioid Consumption(intraoperative)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

d sessler

Professor & Chair

The Cleveland Clinic

研究点 (1)

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