跳至主要内容
临床试验/NCT03271593
NCT03271593已完成不适用

Impact of Rotavirus Vaccination on Hospital Pressures at a Large Paediatric Hospital in the UK: an Ecological Study

GlaxoSmithKline0 个研究点目标入组 1 人开始时间: 2015年11月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1
主要终点
Change in bed day occupancy (BDO) rates

研究概览

简要总结

The impact of rotavirus vaccination on the burden of disease has been well documented. However, the anticipated reduction in hospital pressures has yet to be described. This study will provide quantitative measures of hospital pressure prior to and post vaccine introduction, provide a template for future hospital pressures studies related to vaccine introduction and provide measures which could be used in an economic evaluation.

研究设计

研究类型
Observational
观察模型
Ecologic Or Community
时间视角
Retrospective

入排标准

年龄范围
— 至 15 Years(Child)
性别
All
接受健康志愿者

入选标准

  • All children aged ≤15 years being hospitalised (with overnight stay or day clinic) for whatever reason during the study period

排除标准

  • 未提供

结局指标

主要结局

Change in bed day occupancy (BDO) rates

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

BDO rate is measured as the number of bed days occupied divided by the total number of bed days available in a ward during a fixed time period. BDO rate will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

Change in rate of nosocomial infections (NOSO)

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

NOSO rate is measured as positive test from a test taken \>2 days after admission. NOSO rate will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

Change in number of rotavirus gastroenteritis (RVAG) tests taken

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

RVAG rate will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

Change in turnover (TO) rates

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

TO rate is the change in average hospital duration measured as average number of days stay per admission. TO rate will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

Change in early unplanned readmission (UR) rates

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

UR rate (within 7 days after discharge) is measured as the number of readmissions ≤7 days after discharge (x100) divided by the total number of discharges. UR rate will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

Change in number of positive test results

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

Number of positive RVAG test results will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

Change in rate of hospitalization in children less that 5 years old

时间窗: During the study observation period of 15 years (1st July 2000 - 30th June 2015)

Change in rate of hospitalization (in children less that 5 years old) will be measured in overall admissions, admissions for infectious disease only, admissions for gastro-enteritis only, admissions for rotavirus induced gastro-enteritis only

次要结局

  • Development of a Quality of Care (QoC) score(During the study observation period of 15 years (1st July 2000 - 30th June 2015))

研究者

申办方类型
Industry
责任方
Sponsor

相似试验