on-invasive lung function measurements in infants using Forced Oscillation Technique and diaphragm electromyography.

Completed

• Conditions: 10028971; respiratory distress syndrome; Respiratory insufficiency

• Registration Number: NL-OMON49917
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

* Standard monitoring used with ECG electrodes (25/26 weeks postmenstrual age
and older)
* Intubated due to respiratory failure and and ventilated for >24h with Fabian
HFOi neonatal ventilator with an operational FOT modality
* Written parental/guardian informed consent

Exclusion Criteria

Congenital anomalies that prevent the execution of a dEMG measurement
Asphyxiated infants with therapeutical hypothermia
Receiving nitric oxide therapy
Intubated as part of an end of life decision/ceasing of treatment
Intubation as a consequence of non-pulmonary related surgical intervention

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Reactance values measured with FOT and diaphragm activity measured with dEMG.<br /><br>Both techniques are aimed at examination of lung function over time.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>See primary study parameters</p><br>