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临床试验/NCT07623590
NCT07623590招募中不适用

Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography

Centre Hospitalier Saint Joseph Saint Luc de Lyon2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年4月7日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
30
试验地点
2

研究概览

简要总结

Patients with acute respiratory distress syndrome are placed on mechanical ventilation, and the adjustment of ventilator parameters is an important step in their care, in particular positive expiratory pressure, applied at the end of breathing.

The goal of this study is to learn if continuous anterior chest compression works as well as electrical impedance tomography for positive expiratory pressure titration.

Researchers will compare the two methods for each patient, in a randomly determined order : continuous anterior chest compression and electrical impedance tomography.

Participants will :

  • have a pep titration with both techniques
  • be included in the study for 28 days

详细描述

Personalizing the PEEP level is an important step in ventilator adjustment in ARDS patients.

The investigators have developed a simple, low-cost method to detect overdistension of the lung, consisting of applying manual compression to the anterior aspect of the patient's thorax, and observing whether the ventilator pressure increases or decreases.

The investigators hypothesize that with this simple method it is possible to determine the PEEP level which corresponds to that determined with EIT.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • Moderate to severe ARDS according to the Berlin criteria
  • Patient receiving sedation and continuous curarization
  • Free and informed consent from the patient or their loved one

排除标准

  • Pneumothorax
  • Chest trauma in the last 3 months
  • Uncontrolled shock (noradrenaline > 5 mg/h)
  • Pregnant or breastfeeding woman
  • Protected adult within the meaning of the law
  • Lack of social security
  • Patient under AME

研究者

发起方
Centre Hospitalier Saint Joseph Saint Luc de Lyon
申办方类型
Other
责任方
Sponsor

研究点 (2)

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