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临床试验/NCT06028061
NCT06028061已完成不适用

Evaluation of The Postoperative Analgesic Effectivity of Quadratus Lumborum Block III With Adjuvant on Patients Undergoing Laparoscopic Cholecystectomy Surgery : A Randomised Controled Study

Gaziosmanpasa Research and Education Hospital2 个研究点 分布在 2 个国家目标入组 83 人开始时间: 2023年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
83
试验地点
2
主要终点
Total amount of opioid requirements

研究概览

简要总结

İn recent years abdominal wall blocks are widely used for to reduce intraoperative anesthetic recuirements and postoperative analgesia.Quadratus lumborum blocks are one of the abdominal wall blocks to used at laparoscopic cholecystectomy.Conventionally adjuvants used to improve and prolonged the effect of periferic nerve, spinal and abdominal blocks.İn this study investigators will evaluate the effectiveness of adjuvants at quatratus lumborum block at patient underwent laparoscopic cholecystectomy.

详细描述

Laparoscopic approach in cholecystectomy surgery is frequently preferred because of its advantages in systemic complications, morbidity, mortality and hospital stay. Pain is one of the important causes of late discharge after surgery. Laparoscopic cholecystectomy surgery requires a multimodal analgesia approach because of its multiple pain components.Regional analgesia techniques are effective in reducing the side effects such as intraoperative opioid use, postoperative pain and nausea and vomiting. Quadratus lumborum III block is a regional technique performed for multimodal analgesia.Adjuvants are known to improve the analgesic efficacy and prolonge the effect of the periferic and central nerve blocks.The aim of this study is to determine the effectiveness of adding adjuvant at quadratus lumborum block for patients who underwent laparoscopic cholecystectomy.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Double (Participant, Care Provider)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • American Society of Anesthesiologists physical statusⅠ-II

排除标准

  • Inclusion Criteria:
  • 18-65 years of age
  • American Society of Anesthesiologists physical statusⅠ-II
  • Exclusion Criteria:
  • local anesthetic allergy
  • Infection at the procedure site Body Mass Index >35 kg/m2 Anticoagulant use with bleeding disorder Chronic analgesia and opioid use with mental and psychiatric disorders Contraindications to regional anesthesia several lung and heart disease

结局指标

主要结局

Total amount of opioid requirements

时间窗: within 24 hours after the surgery

The total tramadol use of the patients in 24 hours will be recorded.

rescue analgesia

时间窗: within 24 hours after the surgery

The rescue analgesia requirement and time of the need of the rescue analgesia requirement

次要结局

  • intraoperative remifentanil consumption(during operation procedure])
  • side effects such as nausea, vomiting and shoulder pain(within 24 hours after the surgery)
  • Visual Analogue Scale values(at 1st, 4th,8th 12th and 24th hours after the surgery])

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

SERPİL ŞEHİRLİOĞLU

MD

Gaziosmanpasa Research and Education Hospital

研究点 (2)

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